Romero-Márquez, Jose M. and Navarro-Hortal, María D. and Forbes-Hernández, Tamara Y. and Varela-López, Alfonso and Puentes, Juan G. and Sánchez-González, Cristina and Sumalla Cano, Sandra and Battino, Maurizio and García-Ruiz, Roberto and Sánchez, Sebastián and Quiles, José L. UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, sandra.sumalla@uneatlantico.es, maurizio.battino@uneatlantico.es, UNSPECIFIED, UNSPECIFIED, jose.quiles@uneatlantico.es (2024) Effect of olive leaf phytochemicals on the anti-acetylcholinesterase, anti-cyclooxygenase-2 and ferric reducing antioxidant capacity. Food Chemistry, 444. p. 138516. ISSN 03088146
|
Text
1-s2.0-S030881462400164X-main.pdf Available under License Creative Commons Attribution. Download (2MB) | Preview |
Abstract
In this study, the phytochemical profile of fifty olive leaves (OL) extracts from Spain, Italy, Greece, Portugal, and Morocco was characterized and their anti-cholinergic, anti-inflammatory, and antioxidant activities were evaluated. Luteolin-7-O-glucoside, isoharmnentin, and apigenin were involved in the acetylcholinesterase (AChE) inhibitory activity, while oleuropein and hydroxytyrosol showed noteworthy potential. Secoiridoids contributed to the cyclooxygenase-2 inhibitory activity and antioxidant capacity. Compounds such as oleuropein, ligstroside and luteolin-7-O-glucoside, may exert an important role in the ferric reducing antioxidant capacity. It should be also highlighted the role of hydroxytyrosol, hydroxycoumarins, and verbascoside concerning the antioxidant activity. This research provides valuable insights and confirms that specific compounds within OL extracts contribute to distinct anti-cholinergic, anti-inflammatory, and anti-oxidative effects.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Cholinergic; AChE; COX; Inflammation; Iron; Oxidative stress; Olive; Leaves |
| Subjects: | Subjects > Nutrition |
| Divisions: | Europe University of Atlantic > Research > Scientific Production Ibero-american International University > Research > Scientific Production |
| Depositing User: | Sr Bibliotecario |
| Date Deposited: | 12 Feb 2024 11:10 |
| Last Modified: | 12 Feb 2024 11:10 |
| URI: | http://repositorio.funiber.org/id/eprint/10843 |
Actions (login required)
 |
View Item |
