Cea-Pavez, Inés and Manteca-Bautista, David and Morillo-Gomar, Alejandro and Quirantes-Piné, Rosa and Quiles, José L. UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, jose.quiles@uneatlantico.es (2024) Influence of the Encapsulating Agent on the Bioaccessibility of Phenolic Compounds from Microencapsulated Propolis Extract during "In Vitro" Gastrointestinal Digestion. Foods, 13 (3). p. 425. ISSN 2304-8158
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Abstract
The aim of this work is to develop different encapsulated propolis ingredients by spray-drying and to evaluate their bioaccessibility using simulated in vitro digestion. To achieve these goals, first, microparticles of a propolis extract with inulin as the coating polymer were prepared under the optimal conditions previously determined. Then, a fraction of inulin was replaced with other encapsulating agents, namely sodium alginate, pectin, and chitosan, to obtain different ingredients with controlled release properties in the gastrointestinal tract. The analysis of the phenolic profile in the propolis extract and microparticles showed 58 compounds tentatively identified, belonging mainly to phenolic acid derivatives and flavonoids. Then, the behavior of the free extract and the formulated microparticles under gastrointestinal conditions was studied through an in vitro gastrointestinal digestion process using the INFOGEST protocol. Digestion of the free extract resulted in the degradation of most compounds, which was minimized in the encapsulated formulations. Thus, all developed microparticles could be promising strategies for improving the stability of this bioactive extract under gastrointestinal conditions, thereby enhancing its beneficial effect.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | propolis; encapsulation; spray-drying; bioaccessibility; in vitro gastrointestinal digestion; HPLC-ESI-QTOF-MS/MS |
| Subjects: | Subjects > Nutrition |
| Divisions: | Europe University of Atlantic > Research > Scientific Production |
| Depositing User: | Sr Bibliotecario |
| Date Deposited: | 14 Mar 2024 08:59 |
| Last Modified: | 14 Mar 2024 08:59 |
| URI: | http://repositorio.funiber.org/id/eprint/11260 |
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