Giampieri, Francesca and Quiles, José L. and Orantes-Bermejo, Francisco J. and Gasparrini, Massimiliano and Forbes-Hernandez, Tamara Y. and Sánchez-González, Cristina and Llopis, Juan and Rivas-García, Lorenzo and Afrin, Sadia and Varela-López, Alfonso and Cianciosi, Danila and Reboredo-Rodriguez, Patricia and Fernández-Piñar, Cristina Torres and Caderón Iglesia, Rubén and Ruiz Salces, Roberto and Aparicio Obregón, Silvia and Crespo-Álvarez, Jorge and Dzul Lopez, Luis and Xiao, Jianbo and Battino, Maurizio UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, ruben.calderon@uneatlantico.es, roberto.ruiz@uneatlantico.es, silvia.aparicio@uneatlantico.es, jorge.crespo@uneatlantico.es, luis.dzul@unini.edu.mx, UNSPECIFIED, maurizio.battino@uneatlantico.es (2018) Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties? Food and Chemical Toxicology, 112. pp. 126-133. ISSN 0278-6915
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Abstract
During the process of beeswax recycling, many industrial derivatives are obtained. These matrices may have an interesting healthy and commercial potential but to date they have not been properly studied. The aim of the present work was to evaluate the proximal and phytochemical composition, the antioxidant capacity and cytotoxic effects of two by-products from beeswax recycling process named MUD 1 and MUD 2 on liver hepatocellular carcinoma. Our results showed that MUD 1 presented the highest (P < .05) fiber, protein, carbohydrate, polyphenol and flavonoid concentration, as well as the highest (P < .05) total antioxidant capacity than the MUD 2 samples. MUD1 exerted also anticancer activity on HepG2 cells, by reducing cellular viability, increasing intracellular ROS levels and affecting mitochondrial functionality in a dose-dependent manner. We showed for the first time that by-products from beeswax recycling process can represent a rich source of phytochemicals with high total antioxidant capacity and anticancer activity; however, further researches are necessary to evaluate their potentiality for human health by in vivo studies.
| Item Type: | Article |
|---|---|
| Commentary on: | Eprints 0 not found. |
| Uncontrolled Keywords: | Honey; Beeswax; Food waste; Recycling process; Chemical and phytochemical composition; Biological properties. |
| Subjects: | Subjects > Biomedicine |
| Divisions: | Europe University of Atlantic > Research > Scientific Production Ibero-american International University > Research > Scientific Production |
| SWORD Depositor: | Users 0 not found. |
| Depositing User: | Sr Bibliotecario |
| Date Deposited: | 20 May 2021 10:59 |
| Last Modified: | 19 Jan 2022 15:52 |
| URI: | http://repositorio.funiber.org/id/eprint/131 |
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- Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties? (deposited 20 May 2021 10:59) [Currently Displayed]
Commentary/Response Threads
- Giampieri, Francesca and Quiles, José L. and Orantes-Bermejo, Francisco J. and Gasparrini, Massimiliano and Forbes-Hernandez, Tamara Y. and Sánchez-González, Cristina and Llopis, Juan and Rivas-García, Lorenzo and Afrin, Sadia and Varela-López, Alfonso and Cianciosi, Danila and Reboredo-Rodriguez, Patricia and Fernández-Piñar, Cristina Torres and Caderón Iglesia, Rubén and Ruiz Salces, Roberto and Aparicio Obregón, Silvia and Crespo-Álvarez, Jorge and Dzul Lopez, Luis and Xiao, Jianbo and Battino, Maurizio Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties? (deposited 20 May 2021 10:59) [Currently Displayed]
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