Performance of the 4C and SEIMC scoring systems in predicting mortality from onset to current COVID-19 pandemic in emergency departments

de Santos Castro, Pedro Ángel and del Pozo Vegas, Carlos and Pinilla Arribas, Leyre Teresa and Zalama Sánchez, Daniel and Sanz-García, Ancor and Vásquez del Águila, Tony Giancarlo and González Izquierdo, Pablo and de Santos Sánchez, Sara and Mazas Pérez-Oleaga, Cristina and Dominguez Azpíroz, Irma and Elío Pascual, Iñaki and Martín-Rodríguez, Francisco UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, cristina.mazas@uneatlantico.es, irma.dominguez@unini.edu.mx, inaki.elio@uneatlantico.es, UNSPECIFIED (2024) Performance of the 4C and SEIMC scoring systems in predicting mortality from onset to current COVID-19 pandemic in emergency departments. Scientific Reports, 14 (1). ISSN 2045-2322

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Abstract

The evolution of the COVID-19 pandemic has been associated with variations in clinical presentation and severity. Similarly, prediction scores may suffer changes in their diagnostic accuracy. The aim of this study was to test the 30-day mortality predictive validity of the 4C and SEIMC scores during the sixth wave of the pandemic and to compare them with those of validation studies. This was a longitudinal retrospective observational study. COVID-19 patients who were admitted to the Emergency Department of a Spanish hospital from December 15, 2021, to January 31, 2022, were selected. A side-by-side comparison with the pivotal validation studies was subsequently performed. The main measures were 30-day mortality and the 4C and SEIMC scores. A total of 27,614 patients were considered in the study, including 22,361 from the 4C, 4,627 from the SEIMC and 626 from our hospital. The 30-day mortality rate was significantly lower than that reported in the validation studies. The AUCs were 0.931 (95% CI: 0.90–0.95) for 4C and 0.903 (95% CI: 086–0.93) for SEIMC, which were significantly greater than those obtained in the first wave. Despite the changes that have occurred during the coronavirus disease 2019 (COVID-19) pandemic, with a reduction in lethality, scorecard systems are currently still useful tools for detecting patients with poor disease risk, with better prognostic capacity.

Item Type:	Article
Uncontrolled Keywords:	COVID-19 pandemic, Scoring systems, 4C mortality score, SEIMC score, Mortality, Emergency department
Subjects:	Subjects > Biomedicine
Divisions:	Europe University of Atlantic > Research > Scientific Production Fundación Universitaria Internacional de Colombia > Research > Scientific Production Ibero-american International University > Research > Scientific Production Ibero-american International University > Research > Scientific Production Universidad Internacional do Cuanza > Research > Scientific Production University of La Romana > Research > Scientific Production
Depositing User:	Sr Bibliotecario
Date Deposited:	12 Dec 2024 09:16
Last Modified:	12 Dec 2024 09:16
URI:	http://repositorio.funiber.org/id/eprint/15624

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