Nacka-Aleksić, Mirjana and Pirković, Andrea and Vilotić, Aleksandra and Bojić-Trbojević, Žanka and Jovanović Krivokuća, Milica and Giampieri, Francesca and Battino, Maurizio and Dekanski, Dragana UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es, UNSPECIFIED (2022) The Role of Dietary Polyphenols in Pregnancy and Pregnancy-Related Disorders. Nutrients, 14 (24). p. 5246. ISSN 2072-6643
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Abstract
Polyphenols are a group of phytochemicals with extensive biological functions and health-promoting potential. These compounds are present in most foods of plant origin and their increased widespread availability through the intake of nutritional supplements, fortified foods, and beverages, has also led to increased exposure throughout gestation. In this narrative review, we focus on the role of polyphenols in both healthy and pathological pregnancy. General information related to their classification and function is followed by an overview of their known effects in early-pregnancy events, including the current insights into molecular mechanisms involved. Further, we provide an overview of their involvement in some of the most common pregnancy-associated pathological conditions, such as preeclampsia and gestational diabetes mellitus. Additionally, we also discuss the estimated possible risk of polyphenol consumption on pregnancy outcomes. The consumption of dietary polyphenols during pregnancy needs particular attention considering the possible effects of polyphenols on the mechanisms involved in maternal adaptation and fetal development. Further studies are strongly needed to unravel the in vivo effects of polyphenol metabolites during pregnancy, as well as their role on advanced maternal age, prenatal nutrition, and metabolic risk of the offspring.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | polyphenols; early pregnancy; trophoblast; gestational diabetes mellitus; preeclampsia |
| Subjects: | Subjects > Nutrition |
| Divisions: | Europe University of Atlantic > Research > Scientific Production |
| Depositing User: | Sr Bibliotecario |
| Date Deposited: | 12 Dec 2022 08:56 |
| Last Modified: | 17 Jul 2023 10:24 |
| URI: | http://repositorio.funiber.org/id/eprint/5020 |
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