Romero-Márquez, Jose M. and Varela-López, Alfonso and Navarro-Hortal, María D. and Badillo-Carrasco, Alberto and Forbes-Hernández, Tamara Y. and Giampieri, Francesca and Dominguez Azpíroz, Irma and Madrigal-Hoyos, Lorena and Battino, Maurizio and Quiles, José L. UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, irma.dominguez@uneatlantico.es, lorena.madrigal@uneatlantico.es, maurizio.battino@uneatlantico.es, jose.quiles@uneatlantico.es (2021) Molecular Interactions between Dietary Lipids and Bone Tissue during Aging. International Journal of Molecular Sciences, 22 (12). p. 6473. ISSN 1422-0067
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Abstract
Age-related bone disorders such as osteoporosis or osteoarthritis are a major public health problem due to the functional disability for millions of people worldwide. Furthermore, fractures are associated with a higher degree of morbidity and mortality in the long term, which generates greater financial and health costs. As the world population becomes older, the incidence of this type of disease increases and this effect seems notably greater in those countries that present a more westernized lifestyle. Thus, increased efforts are directed toward reducing risks that need to focus not only on the prevention of bone diseases, but also on the treatment of persons already afflicted. Evidence is accumulating that dietary lipids play an important role in bone health which results relevant to develop effective interventions for prevent bone diseases or alterations, especially in the elderly segment of the population. This review focuses on evidence about the effects of dietary lipids on bone health and describes possible mechanisms to explain how lipids act on bone metabolism during aging. Little work, however, has been accomplished in humans, so this is a challenge for future research.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Dietary lipids; Hallmarks of aging; Oxidative stress; Saturated fat diet |
| Subjects: | Subjects > Biomedicine |
| Divisions: | Europe University of Atlantic > Research > Scientific Production Ibero-american International University > Research > Scientific Production |
| Depositing User: | Sr Bibliotecario |
| Date Deposited: | 08 Mar 2022 13:20 |
| Last Modified: | 07 Jul 2023 08:01 |
| URI: | http://repositorio.funiber.org/id/eprint/522 |
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