Rivas-García, Lorenzo and Romero-Márquez, Jose M. and Navarro-Hortal, M.D. and Esteban-Muñoz, Adelaida and Giampieri, Francesca and Sumalla Cano, Sandra and Battino, Maurizio and Quiles, José L. and Llopis, Juan and Sánchez-González, Cristina UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, UNSPECIFIED, sandra.sumalla@uneatlantico.es, UNSPECIFIED, jose.quiles@uneatlantico.es, UNSPECIFIED, UNSPECIFIED (2022) Unravelling potential biomedical applications of the edible flower Tulbaghia violacea. Food Chemistry, 381. p. 132096. ISSN 03088146
Full text not available from this repository.Abstract
Traditionally, edible flowers have been used as foods and for therapeutic purposes, today they have gained importance due to their bioactive compounds such as flavonols, anthocyanins or other phenolic compounds, which give them potential for biomedical applications. This work evaluated a methanolic extract of Tulbaghia violacea. Eleven individual phenolic compounds were found and quantified by mass spectrometry in the extract. Antioxidant activity tests (TEAC, FRAP and DPPH) and other characterization parameters were assayed (total phenolic content and total flavonoid content). In vitro studies showed antitumoral activity against ovarian tumoral cells mediated by the induction of non-dependent caspase cell death and by the activation of reactive oxygen species. The effect of the extract against features of Alzheimer disease was in vivo assayed in Caenorhabditis elegans. Tulbaghia extract led to a reduction in the 1–42 beta amyloid peptide formation and prevented oxidative stress. These results suggested that Tulbaghia violacea could be a new source of phenolic compounds for nutraceuticals and functional food development.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Flower; Quercetin; Autophagy; ROS; Antioxidants; Alzheimer disease |
| Subjects: | Subjects > Nutrition |
| Divisions: | Europe University of Atlantic > Research > Scientific Production |
| Depositing User: | Sr Bibliotecario |
| Date Deposited: | 15 Mar 2022 12:55 |
| Last Modified: | 18 Jul 2023 08:00 |
| URI: | http://repositorio.funiber.org/id/eprint/567 |
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